The new gong was announced on Wednesday to celebrate the competition’s most creative forces, with the winner to be determined by number of assists.
Title-winner De Bruyne is already locked in a six-way battle to be named the PFA Player of the Year, with Liverpool star Mohamed Salah considered his strongest rival.
But the Manchester City midfielder has a tighter grip on the new award.
De Bruyne is the clear leader with 15 assists and four fixtures still to come, followed by City team-mates Leroy Sane (12) and David Silva (11).
Tottenham midfielder Dele Alli is ranked fourth on 10 assists, while a further four - including Salah - are level on nine.