DayQuil ingredients include a fever and pain reducer (acetaminophen), cough suppressant (dextromethorphan), and decongestant (phenylephrine). The medicine comes in a gel cap and liquid formulas.

This article discusses DayQuil ingredients. It also explains how to take DayQuil, its potential side effects, and its interactions.

DayQuil Ingredients

DayQuil is available in either a gel cap or syrup formulation. Both are orange-colored (in contrast to their nighttime counterpart, NyQuil, which is green). The syrup has a sweetened orange flavor with an antiseptic aftertaste.

DayQuil contains the following three active ingredients per 15-milliliter (mL) dose:

Acetaminophen 325 milligrams (mg; pain reliever/fever reducer) Dextromethorphan 10 mg (cough suppressant) Phenylephrine 5 mg (nasal decongestant)

Inactive Ingredients

The inactive ingredients in DayQuil include:

FD&C Red No. 40FD&C Yellow No. 6GelatinGlycerin Polyethylene glycolPovidonePropylene glycolPurified waterSorbitol specialTitanium dioxide

The dosage of DayQuil varies by formulation. For the standard syrup formulation, the recommended dosage is as follows:

Adults and children over 12: 2 tablespoons (30 ml) every four hours with no more than six doses per 24 hoursChildren ages six to 12: 1 tablespoon (15 ml) every four hours with no more than five doses per 24 hours

DayQuil should not be used in children under six unless under the direction of a pediatrician.

Side Effects and Considerations

While DayQuil is considered safe if used as directed, it can cause nervousness, dizziness, or sleepiness in some and should be avoided in the following circumstances:

DayQuil can cause liver damage in people who drink more than three alcoholic beverages per day. Do not take DayQuil with other medications containing acetaminophen. Taking excessive acetaminophen may cause liver damage even in non-drinkers. Do not take DayQuil if you are taking monoamine oxidase inhibitors (MAOIs) or have taken one in the past two weeks. MAOIs are a class of drugs used to treat depression, anxiety, and other mood disorders. You should stop taking DayQuil and call your healthcare provider if your cold or flu symptoms worsen, last for more than seven days, or are accompanied by a fever lasting for more than three days. The same rules apply to children if the cold or flu symptoms last more than five days.

Drug Effectiveness of DayQuil

While the acetaminophen component of DayQuil is effective in treating cold symptoms such as headache and fever, a 2010 study from Wake Forest University Baptist Medical Center suggested that ibuprofen is a far superior option for both adults and children.

Acetaminophen is better known by the brand name Tylenol. Ibuprofen, meanwhile, is marketed under the brand names Advil and Motrin, among others.

In terms of cough relief, the jury remains largely split. A study conducted in 2012 reviewed data from 26 randomized controlled trials and found that OTC cough formulations, including DayQuil, provided no better or worse relief than receiving no treatment.